Metabolism of prostacyclin in blood vessels
نویسندگان
چکیده
منابع مشابه
Blood Vessels Aging Is Associated With Reduced Prostacyclin-Mediated Dilation in the Human Forearm
Aging is associated with reduced endothelial function. There is indirect evidence for reduced prostacyclin (PGI2)-mediated vasodilation with aging, but it is unknown whether this is because of reduced dilation to PGI2 or altered production. In addition, the contribution of endothelial NO to PGI2-mediated dilation is unknown. Using plethysmography to determine forearm blood flow, we studied the ...
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Labeled and unlabeled prostacyclin and 6-keto-PGF1, were infused into healthy volunteers; urine was chromatographed on different systems including high pressure liquid chromatography. The peaks obtained by the latter method were derivatized to the methoxime methyl ester trimethyl silyl ether and analyzed by gasliquid chromatography-mass spectrometry. After infusion of prostacyclin the follo...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 1978
ISSN: 0021-9258
DOI: 10.1016/s0021-9258(17)30301-0